Triplets Huey (usually dressed in red), Dewey (blue), and Louie (green) are pre-teen boys, full of energy, which sometimes causes them to act before thinking. Although sometimes mischievous, they rarely mean any harm, and are proud Junior Woodchucks. Coming to live with their uncle Scrooge, the boys soon re-juvenile him, and causes the household to grow even bigger, as Scrooge hire Mrs. Beakley as their nanny, and Beakley brings along her young granddaughter, Webby. Although the boys initially are sceptic of having a younger girl join their adventures, they get used to her, and most of the time they go well together with her.
Aside from the fact that they dress in different colors, the boys seem basically identical and inseparable. However, occasionally one stands out among his sibling: Huey is shown to have notable marble playing skills in "Pearl of Wisdom", Dewey discovers he has a talent as a salesman in "Much Ado About Scrooge", and Louie, in a rare example of one of the nephews wanting to be unique, shows signs of being somewhat smarter than his brothers in "Duck in the Iron Mask".